The New Way To Soothe Sensitive & Irritated Skin

by Gio

niod modulating glucosides review

Niod Modulating Glucosides…

Gluco…what? Since when do you need a chemistry degree to buy skincare? Like, would you even pick it off the shelf if you had no idea what it did?

Probably not. And that’s a shame. Cos if you have eczema, rosacea, sensitive skin that gets all red and irritated easily or just upgraded your retinol fix, Niod Modulating Glucosides is your new BFF.

It soothes signs of irritation, like redness, itching and discomfort. About time, isn’t it?

Here’s how it works:

Key Ingredients In Niod Modulating Glucosides

Modulating Glucosides

What the heck is this new skincare sorcery?

Modulating glucosides are old friends, like green and rosemary, joined to a glucose module. Studies show that together they can reduce inflammation and heal treat inflammatory skin conditions like rosacea.

Let’s take a closer look at them:

And that’s just the tip of the iceberg, my smart friend. 🙂

Related: How Green Tea Helps You Fight Wrinkles, Sun Damage And Inflammation

More Skin Soothers!

Modulating glucosides are the stars of the show but there are plenty more soothing ingredients in Niod Modulating Glucosides that can reduce inflammation. Let’s take a look at a few of them:

I could go on but I don’t want to overwhelm you.

Related: Why Chamomile Is A Godsend For Irritated Skin

Skin-Identical Ingredients

When skin is irritated, it usually means its protective barrier is damaged here and there. Those little cracks in your skin’s shield let moisture evaporate so it gets even drier and allows germs and other enemies in so it gets even more irritated.

That’s why all those soothing goodies alone aren’t enough. Your skin also needs bandaids to patch up the holes. In skincare lingo, they’re called skin-identical ingredients: because they’re identical to the building blocks that make up your skin’s protective barrier, they can easily fill the cracks and heal your skin.

Niod Modulating Glucoside has its fair share of skin-identical ingredients. I’ll mention just a few cos I don’t want this to turn into a boring science lesson:

Related: Why You Should Add Amino Acids To Your Skincare Routine

Superoxide Dismutase

Last one, I promise! (Gosh, Niod Modulating Glucoside is so packed with goodies, I could go on forever).

Superoxide dismutase deserves a special mention because it’s the most powerful antioxidant out there. Really.

Superoxide dismutase (SOD) is an antioxidant enzyme (an enzyme that acts like an antioxidant) that destroys superoxide radical, the worst type of free radical ever.

If you want to keep wrinkles off your face, you want this stuff in your skincare routine.

Just don’t use it alone. The more antioxidants you use, the more types of free radicals you destroy. Thankfully, this serum is packed with anti-inflammatory ingredients that double up as antioxidants so you’re covered.

Related: Is Superoxide Dismutase The Most Powerful Antioxidant Of All? 

Let’s Put It To The Test: Personal Use & Opinion

Yellow in colour, Niod Modulating Glucosides has a lightweight texture that sinks immediately into the skin without leaving a greasy residue behind.

Now, I’m lucky I have resistant skin that rarely gets irritated so I can’t personally vouch how well it treats eczema, rosacea or just a bad case of itching or irritation.

(I know, I’m not the best person to review this. I just wanted to try it cos the science behind it is SO fascinating).

But, I’ve recently upped my dose of retinol and that usually means some peeling and flaking. Well, Niod Modulating Glucosides made the transition much easier on my skin.

I’ve had no dryness. No redness. No irritation. Just a little peeling, but nothing compared to how bad it was in the past.

I’m definitely keeping this at hand in case my skin gets a sunburn or an irritation (touch wood!). If you have sensitive skin or your skin is always red, get yourself a bottle and make it a part of your daily routine.

To get the most out of it, use it on clean skin or after exfolation/liquidy toner. The closer to the skin it gets, the better and faster it’ll work.

Available at: £21.00 at Niod

Have you tried Niod Modulating Glucosides? Share your experience in the comments below.

Ingredients: Aqua (Water), Squalane, Isodecyl Neopentanoate, Glycerin, Caprylic/Capric Triglyceride, Pentylene Glycol, Propanediol, Hexyldecanol, Bisabolol, Butylene Glycol, Epigallocatechin Gallatyl Glucoside, Rosmarinyl Glucoside, Caffeyl Glucoside, Gallyl Glucoside, Tetrasodium Tetracarboxymethyl Naringeninchalcone, Hydroxymethoxyphenyl Decanone, 4-t-Butylcyclohexanol, Cetylhydroxyproline Palmitamide, Hydroxyphenyl Propamidobenzoic Acid, Palmitoyl tripeptide-8, Superoxide Dismutase, Sodium PCA, PCA, Arginine, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Aspartic Acid, Sodium Lactate, Mirabilis Jalapa Callus Extract, Tasmannia Lanceolata Fruit/Leaf Extract, Zingiber Officinale (Ginger) Root Extract, Curculigo Orchioides Root Extract, Isochrysis Galbana Extract, Brassica Campestris (Rapeseed) Sterols, Stearic Acid, Dextran, Isoceteth-20, Polyacrylate Crosspolymer-6, Xanthan gum, Tocopherol, Propyl Gallate, Tromethamine, Dehydroacetic Acid, 1,2-Hexanediol, Benzyl Alcohol, Phenoxyethanol, Caprylyl Glycol.

PR Sample.



Maria August 1, 2018 - 11:20 am

Oh boy! I was just about to purchase Survival 0 and planned to try Modulating Glucosides during winter, but now I don’t know anymore… I really didn’t realize that Modulating Glucosides can be considered as an antioxidant serum, thought just that might be calming for sensitive skin. Would it be a good antioxidant serum for daytime use? I currently use Missha Time Revolution ampoule as my daytime serum. I’ve gone through few bottles of it and while I’m still enjoying it, I’m tempted to try these Niod serums.

Gio August 5, 2018 - 10:11 am

Maria, a lot of anti-inflammatory ingredients also have antioxidant properties so they do double duty. If you want to fight both inflammation and free radicals, then you can use this during the day. 🙂

Tatiana August 9, 2018 - 5:09 pm

Can I combine with C E Folic ?

Tatiana August 9, 2018 - 5:41 pm

Ops. C E Ferulic

Gio August 16, 2018 - 12:01 pm

Tatiana, yes, you can.

Tatiana October 27, 2018 - 5:57 pm

Hi Gio, is this a good product to use after professional peeling ?
I have sensitive skin planning to have a professional peeling to get rid of my dark sposts. What do you suggest?
I would love to know your routine after peeling, have you write about it?

Gio November 1, 2018 - 4:40 pm

Tatiana, I haven’t written about my post-peeling routine yet. Usually, I just use the same products as always, I just lay off retinol and exfoliation for a few days. But yes, this is a great product to use after a peel, especially if it’s left you with a little redness.

Renata Boyle December 28, 2018 - 4:02 pm

Hi Gio – keep forgetting you do a blog as well as the emails, just got your email today with this product on and have just ordered it for my redness … I was just wondering though, I’ve also just got the EUK 123 and it is very difficult to apply on it’s own as it’s so grainy and difficult to spread, I’ve been mixing it into a Missha repair serum but I know you shouldn’t really mix with other products (especially acids/vit V) – do you think I could add my EUK drops to this modulating glucosides product? I hate it when one product messes up your whole routine lol. Loving your emails, keep them coming, will report back as to whether this reduces my redness.
Best wishes

Gio January 6, 2019 - 1:03 pm

Renata, I hope it’s been working well for you so far. It’s the best product to soothe redness I’ve found so far. 🙂

Mmm, if you have to mix actives, it’s best to mix them with more basic products, like a hyaluronic acid serum or a moisturizer without retinol/acids/actives.

Sharon January 2, 2019 - 10:56 pm

Is there any info on Niod NAAP on this site? Trying do decide if it’s worth the price tag ?

Gio January 12, 2019 - 11:24 am

Sharon, I haven’t tried NAAP yet but it’s on my to-review list. Check back soon!

Fiona January 3, 2019 - 3:49 pm

I’m on my second bottle of this and have found it really helpful in reducing the persistent redness and inflammation from which I’ve suffered for five years now. (NHS dermatologists are unanimous that I do not have acne, allergies or standard-issue rosacea but my skin had for some reason become hyper-sensitive and slow to heal.) Anyway this, used with a few drops of The Ordinary’s borage oil twice a day, has made a noticeable improvement over the course of two months. Excellent for me.

Gio January 12, 2019 - 9:07 am

Fiona, thanks for sharing your experience. So glad it’s working well for you. It’s a miracle in a bottle, isn’t it?

JB February 27, 2019 - 2:03 am

Thanks for the tip! The review is great too, of course. Off to buy all 3 now…

Gio March 1, 2019 - 9:29 am

JB, glad you enjoyed it.

Tracy August 6, 2019 - 10:30 pm

Do I have to incorporate another Ordinary product with this one? I read somewhere you are “supposed to.” Thanks! : )

Gio August 8, 2019 - 2:38 pm

Tracy, I’m not sure I understand the question? This is a great serum for sensitive skin, but you should still use cleanser and sunscreen at least. Not necessarily from The Ordinary.

Ede September 17, 2019 - 12:31 pm

I’ve been using this morning and night for a few months now, in conjunction with a bunch of other NIOD, Hylamide and The Ordinary products. I haven’t found it to reduce the flakiness/peeling I get around my nostrils or on either side of my chin when I use Glycolic or Lactic acid there. They’re the only sensitive areas of my skin, everywhere else you can throw acid at it and it’s fine, but god forbid I get some acid around my nose, it peels for at least a week. I’ve even tried putting it around my nose to act as a barrier when applying acids to the rest of my face, but that didn’t seem to help at all.
I’m also applying it as direct by NIOD – After CAIS and before the Hylauronic complex.
I’ll be finishing the bottle soon, I’m interested to see if there’s any changes once I stop using it.

Ali September 17, 2019 - 5:02 pm

I suffer from Perioral Dermatitis (PD) under the nose bridge which appears as a scaly and tiny red bumpy rash. My dermatologist explained that with PD basically the out barrier of the skin is broken which is causing it to by scaly. However, no itching or any other issues. it has been a constant battle for me as it goes away and then comes back. Do you think this product might help with my condition?

Ali September 17, 2019 - 5:04 pm

Also, would it be safe to use during pregnancy?

Gio October 5, 2019 - 5:09 pm

Ali, this can help soothe the redness and irritation, but it won’t repair your broken protective barrier. Yes, it’s safe during pregnancy.

Connie April 5, 2020 - 5:00 pm

I have sensitive skin and about twice a year I have a flare up of Rosacea which can be tough to treat. I have been using NIOD’S MG Serum for over a year. I have a brand new bottle waiting for me for when I use up my current bottle. It works great for me and is one of the very few products I use when I have a flare up. I love it. It does exactly what it promises to do.


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